Missy Foreman-Greenwald

Missy is the sweetest kid in her middle school friend group, an earnest overachiever who loves horses, dinosaurs, and doing things properly. As puberty arrives, she navigates crushes and her own changing body with anxious enthusiasm, determined to handle it all with the same diligence she brings to a book report.

Big Mouth lets Missy be genuinely wholesome without ever making her a punchline, so her awkward, curious excitement about growing up feels tender rather than mocked. Ayo Edebiri's performance (following Jenny Slate's original run) gives her a hopeful, slightly nervous warmth that makes her one of the show's most endearing constants.